Icon of Sin/Doom Eternal

Background
Near the end of the game, Samuel Hayden informs the Doom Slayer that Khan Maykr is awakening the Icon of Sin as a last-ditch effort to destroy the Earth. To stop this, the Slayer travels to Urdak and confronts the Maykrs as they complete the ritual to awaken the Icon, intending to control it via the mortal heart of the Argenta it used to be. Using a knife given to him by Valen, the Slayer destroys the heart, causing the Icon of Sin to go berserk and travel to Earth independent of the Khan's control. This also breaks the Maykr's pact with Hell, allowing demons to invade Urdak. After slaying Khan Maykr and returning to Earth, the Slayer battles the Icon of Sin atop a skyscraper, destroying the Maykr-made armor protecting it. Once the armor is fully destroyed, the Icon of Sin teleports to a different location; the Slayer pursues it to continue their battle. After a lengthy battle that results in most of the Icon of Sin's flesh being destroyed, it is left weakened enough for the Slayer to climb onto its head and bury the Crucible into its exposed brain, breaking off the blade to kill the Titan for good.